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Thiopurine Calculator

This application allows for the interpretation of drug levels and generates, on the basis of this, individual dosage recommendations in patients with inflammatory bowel disease who use thiopurines.

Publish date: June 2017
Commissioned by: Máxima Pharmaceutical Center

App description

This application allows for the interpretation of drug levels and generates, on the basis of this, individual dosage recommendations in patients with inflammatory bowel disease who use thiopurines. The two main pharmacologically active metabolites of  thiopurines are 6-TGN and 6-MMPR. The measured blood plasma level of these metabolites, as well as their mutual ratio, determine the individual dosage recommendation.

This app was developed in collaboration with Dr. L.J.J. Derijks, hospital pharmacist – clinical pharmacologist.

Functionality



By choosing a drug (thiopurines azathiopurine or 6-mercaptopurine and 6-thioguanine) and method of analysis (Lennard, Dervieux, Erdmann), the thiopurine calculator can generate a dosage recommendation for inflammatory bowel disease.

Functionality

By choosing a drug (thiopurines azathiopurine or 6-mercaptopurine and 6-thioguanine) and method of analysis (Lennard, Dervieux, Erdmann), the thiopurine calculator can generate a dosage recommendation for inflammatory bowel disease.

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With healthcare apps, we aim to take care of healthcare.

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With healthcare apps, we aim to take care of healthcare.

Feel free to contact us!

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